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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGRF2
All Species:
13.03
Human Site:
T770
Identified Species:
31.85
UniProt:
O14827
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14827
NP_008840.1
1237
140764
T770
S
S
S
P
T
T
T
T
Q
S
P
A
A
S
P
Chimpanzee
Pan troglodytes
XP_517672
1237
140775
T770
S
S
S
P
T
T
T
T
Q
S
P
A
A
S
P
Rhesus Macaque
Macaca mulatta
XP_001108408
514
59608
Y94
E
P
L
E
K
Q
H
Y
F
T
V
N
F
S
H
Dog
Lupus familis
XP_852734
1350
152162
T770
C
S
A
S
S
S
P
T
A
T
H
S
P
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P70392
1189
135649
G755
S
S
L
N
S
R
I
G
A
L
D
L
T
N
S
Rat
Rattus norvegicus
Q99JE4
1190
135808
G755
S
S
L
N
S
R
I
G
A
L
D
L
T
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510010
1242
141041
T774
S
S
T
A
S
S
P
T
S
T
F
S
P
A
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEA7
1244
141569
S766
T
T
S
S
S
A
A
S
S
P
T
S
A
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122143
690
76494
D270
S
D
I
S
Q
C
M
D
N
V
H
F
N
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780300
1211
137984
G765
E
T
D
G
G
S
S
G
G
S
G
G
R
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
31.3
87.1
N.A.
91.1
91.2
N.A.
91.2
N.A.
N.A.
85.4
N.A.
N.A.
25.4
N.A.
48.5
Protein Similarity:
100
99.7
36.2
89.2
N.A.
93.5
93.6
N.A.
95.1
N.A.
N.A.
91.6
N.A.
N.A.
37
N.A.
64.7
P-Site Identity:
100
100
6.6
13.3
N.A.
13.3
13.3
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
13.3
53.3
N.A.
26.6
26.6
N.A.
60
N.A.
N.A.
60
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
10
10
0
30
0
0
20
30
20
10
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
10
0
0
20
0
0
10
0
% D
% Glu:
20
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
10
10
0
0
% F
% Gly:
0
0
0
10
10
0
0
30
10
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
30
0
0
0
0
0
0
20
0
20
0
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
0
0
0
0
10
0
0
10
10
20
0
% N
% Pro:
0
10
0
20
0
0
20
0
0
10
20
0
20
0
30
% P
% Gln:
0
0
0
0
10
10
0
0
20
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
20
0
0
0
0
0
0
10
0
0
% R
% Ser:
60
60
30
30
50
30
10
10
20
30
0
30
0
30
20
% S
% Thr:
10
20
10
0
20
20
20
40
0
30
10
0
20
10
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _